Here is another report on the news: The
FDA’s prompt, go-ahead action suggests that the agency isn’t particularly
concerned that this could be a safety issue beyond the combo with fludarabine.
The trial will continue, as it was previously, with a preconditioning regimen
consisting solely of another chemotherapy drug, cyclophosphamide.
As with any new technologies, you can bet there are a lot of
doubts and naysayers out there about the validity and their longevity. But just
remember, great opportunities are always born with doubts and disbelief. If everything
is well established, you think you can get a good price anymore? I guess
everyone would agree Apple is a great company now but how many of you know Apple
has gone through turmoil 7 times close to bankruptcy? Big money is not made
when iPhone/iPad became popular products but when Steve Jobs was kicked out
from Apple years ago. That’s how a great opportunity was created with a
frightening crisis. So investment, especially speculative investment is not
looking for certainty but for a reasonable possibility of success. I’m
convinced we have one for Juno. If it were not, you would not have seen
Celgene spending billions for a deal with Juno. Now GE is also coming
on board to
build a $1 billion business offering vital manufacturing tools for a coming
wave of cell therapies. Why so? Because they estimate sales of cell
therapies will reach $10 billion by 2020 and $30 billion by 2030!
Having said that and regardless how much I believe in CAR-T,
it is still a speculation with substantial risk. As such, I don’t want to
simply buy and hold but structure my positions in such a way that my downside
risk is minimized, in case I’m totally wrong. As I said, I bought stocks
outright after hours when it tanked 30% and I bought call options the next day
when it continued to slid down. So I took the opportunity to sell my stocks
with good profit when it jumped high on Wed and in turn I used my profit to buy
more calls as free long-term positions. For my calls, I partially sold covered
calls to minimize my risk but it won’t totally cap my potential gains.
Considering this won’t be a smooth journey but likely a very bumpy road, one
may also consider to set up a straddle by buying calls and puts at the same
time. If you consider this strategy, it is important to go for the long-term
calls/puts. With sufficient time, I think Juno calls may likely gain several
times from your initial invested money. This is what I’m looking for!
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